Development of Lanthanide-tagged Substrates Towards the Detection of Proteases by Inductively Coupled Plasma-mass Spectrometry (ICP-MS)
Rapid, sensitive and quantitative assays for proteases are of great significance for drug development and in diagnosis of diseases. Herein, we describe work towards a novel assay for the multiplexed detection of proteases using ICP-MS. Protease substrates were synthesized containing a diethylenetria...
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| Language: | en_ca |
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2008
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| Online Access: | http://hdl.handle.net/1807/19310 |