The Role of Rac1 and Rac2 in Determining Bone Quality in Aged and Osteoporotic Female Mouse Models

The osteoclasts, the bone cells responsible for bone degradation, have a crucial role in the age-related bone loss and post-menopause osteoporosis. Rac1 and Rac2, members of the Rho-family of small GTPases, are known for having a key role in osteoclast formation and activity, which could be translat...

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Bibliographic Details
Main Author: Magalhaes, Joyce Kellen Rodrigues de Souza
Other Authors: Glogauer, Michael
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/24266