Investigation of Atypical Binding Behaviours of the SH3 Domain of the Yeast Protein, Fus1p
The yeast Fus1p SH3 domain recognizes non-PXXP motif targets. This is contrary to most SH3 domains, which recognize PXXP-containing sequences. In this thesis, I characterized atypical binding of the Fus1p SH3 domain and provide insight into atypical SH3 domain interactions. I demonstrated that the F...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/24355 |