A Mass Spectrometry Approach to Ligand Identification for Orphan Fly and Human Nuclear Receptors
The nuclear receptor superfamily is responsible for regulating the expression of genes involved in development, reproduction and metabolism. These transcription factors control the expression of their target genes through the binding of small molecule regulators to their ligand binding domains. Cl...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/24844 |