The Role of Dimerization by Escherichia coli HypB in Hydrogenase Biosynthesis

Nickel insertion into the [NiFe]-hydrogenase requires the accessory protein HypB, which is a GTPase. The GTPase domain of Escherichia coli (E. coli) HypB undergoes dimerization in the presence of GTP. To determine the role of HypB dimerization in hydrogenase biosynthesis, a double mutation L242A/L...

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Bibliographic Details
Main Author: Cai, Fang
Other Authors: Zamble, Deborah
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25441