The Role of Dimerization by Escherichia coli HypB in Hydrogenase Biosynthesis
Nickel insertion into the [NiFe]-hydrogenase requires the accessory protein HypB, which is a GTPase. The GTPase domain of Escherichia coli (E. coli) HypB undergoes dimerization in the presence of GTP. To determine the role of HypB dimerization in hydrogenase biosynthesis, a double mutation L242A/L...
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Language: | en_ca |
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2010
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Online Access: | http://hdl.handle.net/1807/25441 |