Defining the Mechanisms by which Palmitoylation Regulates the Localization and Function of RGS4

Regulator of G-protein signalling 4 (RGS4) modulates Gq and Gi signalling at the plasma membrane (PM). It has been demonstrated that the addition of palmitate to cysteine residues is an important regulator of RGS protein localization and function. The family of palmitate transferase enzymes shares a...

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Bibliographic Details
Main Author: Dissanayake, Kaveesh
Other Authors: Heximer, Scott P.
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25554