Examining the Role of Herp in the ER Stress Response of Pancreatic Beta Cells

The unfolded protein response, which is activated during ER stress, counteracts stress conditions by increasing folding capacity and by increasing the degradation of misfolded ER proteins by the ER-Associated Degradation (ERAD) system. Studies using an engineered insulinoma cell line with inducible...

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Bibliographic Details
Main Author: Siva, Madura
Other Authors: Volchuk, Allen
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25803