Examining the Role of Herp in the ER Stress Response of Pancreatic Beta Cells
The unfolded protein response, which is activated during ER stress, counteracts stress conditions by increasing folding capacity and by increasing the degradation of misfolded ER proteins by the ER-Associated Degradation (ERAD) system. Studies using an engineered insulinoma cell line with inducible...
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Language: | en_ca |
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2010
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Online Access: | http://hdl.handle.net/1807/25803 |