Development of a Continuous Density Gradient of Immobilized Probes for Controlling the Stringency of DNA Hybridization

A new format for microfluidic based DNA biosensors is presented in which the biorecognition element (single stranded DNA probes) is immobilized as a continuous density gradient of probes along the length of a microfluidic channel instead of a standard array format commonly used in microarray technol...

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Bibliographic Details
Main Author: Noor, Muhammad Omair
Other Authors: Krull, Ulrich Jorg
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25878