Modulation of Aryl Hydrocarbon Receptor-dependent Transcription by Halogenated Compounds and Pharmaceuticals
The aryl hydrocarbon receptor (AHR) mediates the toxic effects of halogenated aromatic hydrocarbons (HAHs), including 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,4,7,8-pentachlorodibenzofuran and 2,3,7,8-tetrachlorodibenzofuran. Y322 is believed to play a role in binding-independent activation of AHR...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29602 |