Characterization and Modeling of the Remodeling Process that Occurs in Modular Tissue Engineered Constructs Assembled Within Microfluidic Perfusion Chambers

Characterization and Modeling of the Remodeling Process that Occurs in Modular Tissue Engineered Constructs Assembled Within Microfluidic Perfusion Chambers

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Using a modular approach, a vascularized tissue construct is created by embedding functional cells within submillimeter-sized collagen cylinders (modules) while the outside surfaces are seeded with endothelial cells (EC). The void spaces created by randomly packing modules into a container form EC-...

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Bibliographic Details
Main Author: Khan, Omar
Other Authors: Sefton, Michael
Language:en_ca
Published: 2011
Subjects:
tissue engineering
microfluidics
perfusion
endothelial cells
mesenchymal stromal cells
activation
differentiation
remodeling
model
collagen
poloxamine
shear stress
disturbed flow
vascular
modular
0541
0542
Online Access:http://hdl.handle.net/1807/29772

Internet

http://hdl.handle.net/1807/29772

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