Investigation into the Role of CBL-B in Leukemogenesis and Migration

CBL proteins are E3 ubiquitin ligases and adaptor proteins. The mammalian homologs – CBL, CBL-B and CBL-3 show broad tissue expression; accordingly, the CBL proteins play roles in multiple cell types. We have investigated the function of the CBL-B protein in hematopoietic cells and fibroblasts. The...

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Bibliographic Details
Main Author: Badger-Brown, Karla Michelle
Other Authors: Barber, Dwayne
Language:en_ca
Published: 2006
Subjects:
Online Access:http://hdl.handle.net/1807/29946