Transition to Seizure in the CA3 Hippocampal Network: Predominant Preictal GABAergic Potentials, followed by Predominant Ictal Glutamatergic Potentials
The mechanisms underlying the transition to seizure are still unresolved. Proposed mechanisms include excitatory GABAergic drive, loss of interneuron-mediated inhibition, and glutamatergic input potentiation. The objective of this thesis was to investigate the relative contributions of synchronized...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/30134 |