Rhodium-catalyzed Addition of Arylboronic Acids to Nitriles: Application in the Synthesis of Unsymmetrical Polysubstituted Pyridines

Investigations pertaining to the rhodium(I)-catalyzed addition of arylboronic acids to (arylsulfonyl)acetonitriles were undertaken. The resulting carbon-carbon bond forming reaction has led to the efficient synthesis of novel stereoselective (Z)-β-sulfonylvinylamines, which upon acidic hydrolysis, a...

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Bibliographic Details
Main Author: Lau, Chan Tong
Other Authors: Lautens, Mark
Language:en_ca
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1807/31293