Generation and Characterization of Neural Stem Cells Derived from Embryonic Stem Cells using the Default Mechanism
In embryonic stem cells (ESCs) neural differentiation is elicited in the absence of extrinsic signaling in minimal conditions. This ‘default mechanism’ in ESCs produces neural stem cells termed primitive neural stem cells, which can subsequently yield FGF2-dependent definitive neural stem cells (dNS...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/31415 |