Protective Effect of Peroxiredoxin 2 on Oxidative Stress Induced β-cell Toxicity in the Pancreatic β-cell Line MIN6

Type 1 and type 2 diabetes are characterized by an excessive loss of insulin producing β-cells. β-cells are particularly susceptible to increased oxidative stress induced apoptosis due to low expression of major antioxidants. Peroxiredoxin-2 (PRDX2) belongs to a group of antioxidants with antiapopto...

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Bibliographic Details
Main Author: Zhao, Fang
Other Authors: Wang, Qinghua
Language:en_ca
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1807/31662