Roles of Matrix Mechanics in Regulating Aortic Valve Interstitial Cell Pathological Differentiation

Calcific aortic valve disease (CAVD) is associated with increased presence of myofibroblasts, osteoblastic cells and, occasionally, adipocytes and chondrocytes in lesions. The ectopic cell types in diseased valves may be elaborated by an unidentified multipotent progenitor subpopulation within the...

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Bibliographic Details
Main Author: Chen, Jan-Hung
Other Authors: Simmons, Craig Alexander
Language:en_ca
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1807/31716