Structural and Functional Studies of ATP7B, the Copper(I)-transporting P-type ATPase Implicated in Wilson Disease

Copper is an integral component of key metabolic enzymes. Numerous physiological processes depend on a fine balance between the biosynthetic incorporation of copper into proteins and the export of excess copper from the cell. The homeostatic control of copper requires the activity of the copper tr...

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Bibliographic Details
Main Author: Fatemi, Negah
Other Authors: Forman-Kay, Julie Deborah
Language:en_ca
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1807/31746