The Development of Novel Protein Topology Mapping Strategies using Crosslinking, Cyanogen Bromide Cleavage, and Mass Spectrometry
Advances in protein topology mapping methods are urgently needed to complement the wealth of interactome data that is presently being generated at a rapid pace. Chemical crosslinking followed by mass spectrometry (MS) has evolved over the last decade as an attractive method for protein topology and...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/31969 |