Disrupting the Non-specific Interactions between DNA and the Escherichia coli Transcriptional Repressor NikR
The Escherichia coli transcription factor NikR is responsible for nickel-mediated repression of the nik operon. The crystal structure of NikR in complex with its operator sequence provided insight into the mechanistic details of nickel-activated NikR-DNA complex formation. The crystal structure reve...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32475 |