The Role of TLR2 in the Pathogenesis of Kawasaki Disease

Kawasaki disease (KD) is a childhood vasculitis with a predilection for the coronary arteries (CA). The etiology of KD is unknown; however, superantigens (SAg) have been implicated. SAg-activated T cells undergo massive proliferation followed by apoptosis; conversely, in KD these T cells may persist...

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Bibliographic Details
Main Author: Wardinger, Jaimie
Other Authors: Yeung, Rae S. M.
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/32499