Down-regulation of Cytochrome P450 2C8 by 3-methylcholanthrene in Human Hepatocellualar Carcinoma Cell Lines
3-Methylcholanthrene (MC) is a model polycyclic aromatic hydrocarbon that induces cytochrome P450 1A1 (CYP1A1) expression. This laboratory has shown previously that aromatic hydrocarbons, which are important environmental toxicants, down-regulate the expression of rat liver CYP2C11. Recent observati...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32636 |