Pancreatic Alpha-cell Characterization in Healthy and Type 1 Diabetic Mice Employing Organotypic Tissue Slice Preparations

Pancreatic alpha- and beta-cells play vital roles in maintaining glucose homeostasis. While much work has investigated beta-cell biology, alpha-cell research has been scarce. This is due to limitations in conventional methods of alpha-cell preparation, which expose alpha-cells on the islet mantle t...

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Bibliographic Details
Main Author: Ya-Chi, Huang
Other Authors: Herbert, Gaisano
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/32741