Bayesian Hidden Markov Models for finding DNA Copy Number Changes from SNP Genotyping Arrays
DNA copy number variations (CNVs), which involve the deletion or duplication of subchromosomal segments of the genome, have become a focus of genetics research. This dissertation develops Bayesian HMMs for finding CNVs from single nucleotide polymorphism (SNP) arrays. A Bayesian framework to recon...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32794 |