Survivin Gene Therapy using Ultrasound-targeted Microbubble Destruction in a Rat Model of Doxorubicin-induced Cardiomyopathy

With the recent advent of gene therapy, anti-apoptotic therapy has been receiving spotlight as a potential modality to inhibit the deterioration of pump function in the failing heart. We hypothesized that anti-apoptotic therapy using survivin gene delivery will 1) salvage H9c2 cells exposed to doxor...

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Bibliographic Details
Main Author: Lee, Paul Jae-Hyuk
Other Authors: Leong-Poi, Howard
Language:en_ca
Published: 2012
Subjects:
Rat
Online Access:http://hdl.handle.net/1807/33283