Generating Inducible Vector Systems for Controlling Pluripotent Stem Cell Fate
Transgenic manipulation of exogenous and endogenous gene expression in human embryonic stem cells (hESCs) is a powerful approach to decipher the genetic pathways dictating their developmental fate. Presently used genetic tools face limitations including leakiness in inducibility of expression, epige...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33596 |