Investigations into the Significance of the Evolutionary Descent of Prion Genes from Ancestral Zip Transporter
The conformational conversion of the cellular prion protein (PrPC) to PrP scrapie (PrPSc) is a hallmark of prion diseases [1]. The cellular role of PrP and the mechanism of PrPSc neurotoxicity remain largely elusive. Therefore, the identification of new prion-like proteins can assist in revealing th...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33768 |