Functional Analysis of the Pseudoprotease iRhom2 and Nonsense-mediated mRNA Decay Factor Smg1 using Gene Deficient Mice
This work involves the characterization of two genes using mouse models of gene deficiency and thus has two focuses: Focus I: Innate immune responses are vital for pathogen defence but can result in septic shock when excessive. A key mediator of septic shock is TNFα, which is shed into intercellula...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33888 |