Molecular Mechanisms of Glycine Primed NMDA Receptor Internalization

N-Methyl-D-aspartate receptors (NMDARs) are a principal subtype of excitatory ligandgated ion channel with prominent roles in physiology and disease in the mammalian central nervous system (CNS). Activation of NMDARs requires binding of both glutamate and glycine. Apart from its co-agonist action, g...

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Bibliographic Details
Main Author: Han, Lu
Other Authors: Salter, Michael
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/34027