The LNX Family of Multi-PDZ E3 Ligases: Using a Mutagenesis-based Approach to Establish the Role of PDZ Domains in LNX1 Function
LNX1 belongs to a family of multi-PDZ domain containing RING-type E3 ligases. Several interactions have been mapped to its PDZ domains, but the role of each domain in LNX function has not yet been determined. To study individual PDZ domain function in the context of full length protein I generated p...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/35136 |