Effects of Insulin Resistance on Leptin Modulation of Hypothalamic Neurons
Central resistance to the actions of insulin and leptin is strongly associated with obesity and type 2 diabetes mellitus (T2DM). These anorexigenic hormones modulate one another’s actions at the neuronal level. To investigate the cellular events underlying the effect of insulin resistance on leptin...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/35549 |