Insulin Receptor Signaling is Necessary for the Maintenance of Epithelial Phenotype in MCF10A Cells
Obesity is an adverse factor in the development and severity of breast cancer. Obesity is often accompanied by an increase in circulating insulin, which is also associated with poor BC prognosis. Although not expressed in normal breast tissue, the insulin receptor (IR) is highly expressed in BC, the...
| Main Author: | |
|---|---|
| Other Authors: | |
| Language: | en_ca |
| Published: |
2013
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/1807/35599 |