The Expression and Regulation of CYP2D in a Monkey Model of Ethanol and Nicotine Exposure
CYP2D6 metabolizes a range of centrally acting drugs, neurotoxins, and endogenous neurochemicals. Higher levels of brain, but not liver, CYP2D6 have been identified in alcoholics and smokers, suggesting exposure to ethanol and/or nicotine may induce brain CYP2D6. We investigated the independent and...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/35642 |