The Expression and Regulation of CYP2D in a Monkey Model of Ethanol and Nicotine Exposure
CYP2D6 metabolizes a range of centrally acting drugs, neurotoxins, and endogenous neurochemicals. Higher levels of brain, but not liver, CYP2D6 have been identified in alcoholics and smokers, suggesting exposure to ethanol and/or nicotine may induce brain CYP2D6. We investigated the independent and...
Main Author: | |
---|---|
Other Authors: | |
Language: | en_ca |
Published: |
2013
|
Subjects: | |
Online Access: | http://hdl.handle.net/1807/35642 |