Development and Application of High-throughput Chemical Genomic Screens for Functional Studies of Cancer Therapeutics
Chemotherapeutic agents act by targeting rapidly dividing cancer cells. The full extent of their cellular mechanisms, which is essential to balance efficacy and toxicity, is often unclear. In addition, the use of many anticancer drugs is limited by dose-limiting toxicities as well as the development...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/35790 |