The Role of Chloride Channels in Regulation of Pulmonary Artery Smooth Muscle Cell Proliferation

The Role of Chloride Channels in Regulation of Pulmonary Artery Smooth Muscle Cell Proliferation

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Pulmonary arterial hypertension (PAH) is a rare but fatal disease with an annual mortality rate of 15% despite current therapies. Uncontrolled proliferation of pulmonary artery smooth muscle cells (PASMCs) results in adverse vascular remodeling contributing to PAH. Understanding the mechanisms of PA...

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Bibliographic Details
Main Author: Liang, Wenbin
Other Authors: Backx, Peter
Language:en_ca
Published: 2012
Subjects:
Pulmonary arterial hypertension
Pulmonary artery smooth muscle cell
Proliferation
Chloride channel
Cell volume
Membrane potential
RNA interference
Lentivirus
CLC channels
CLC-3
DIDS
DCPIB
0719
Online Access:http://hdl.handle.net/1807/42521

Internet

http://hdl.handle.net/1807/42521

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