The Regulation of RhoGEF LFC by Dyenin Light Chain Tctex-1
Lfc is a guanine nucleotide exchange factor (GEF) that activates the small GTPase RhoA, and its GEF activity is tightly regulated through protein-protein interactions, phosphorylation, and cellular localization. Lfc is anchored to microtubules through its interaction with the dynein light chain Tcte...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/42695 |