Effects of Cadmium on Actin Glutathionylation and Focal Adhesions
The toxic metal ion cadmium (Cd2+) is pro-oxidant and specifically disrupts the actin cytoskeleton in renal mesangial cells. This study investigated the role of Cd2+-mediated redox modulation of actin through protein S-glutathionylation and the effects of cytoskeletal changes on focal adhesions (FAs...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/42739 |