SLIT2 Prevents Renal Ischemia Reperfusion Injury in Mice

The Slit family of secreted proteins act as axonal repellents during embryogenesis. Slit2 via its receptor, Roundabout-1, also inhibits chemotaxis of multiple leukocyte subsets. Using static and microfluidic shear assays, we found that Slit2 inhibited multiple steps required to recruit circulating...

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Bibliographic Details
Main Author: Chaturvedi, Swasti
Other Authors: Robinson, Lisa
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/42902