SLIT2 Prevents Renal Ischemia Reperfusion Injury in Mice
The Slit family of secreted proteins act as axonal repellents during embryogenesis. Slit2 via its receptor, Roundabout-1, also inhibits chemotaxis of multiple leukocyte subsets. Using static and microfluidic shear assays, we found that Slit2 inhibited multiple steps required to recruit circulating...
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Language: | en_ca |
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2012
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Online Access: | http://hdl.handle.net/1807/42902 |