Investigating the Role of ATF6Beta in the ER Stress Response of Pancreatic Beta-cells

Investigating the Role of ATF6Beta in the ER Stress Response of Pancreatic Beta-cells

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Endoplasmic reticulum (ER) stress has been implicated as a causative factor in the development of pancreatic beta-cell dysfunction and death resulting in type 2 diabetes. This thesis examined the role of ATF6beta in the ER stress response of beta-cells. Using an ATF6beta-specific antibody, express...

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Bibliographic Details
Main Author: Odisho, Tanya
Other Authors: Volchuk, Allen
Language:en_ca
Published: 2013
Subjects:
Diabetes
ER stress
Apoptosis
ATF6beta
unfolded protein response
ATF6 signaling pathway
pancreatic beta-cell
0719
Online Access:http://hdl.handle.net/1807/43275

Internet

http://hdl.handle.net/1807/43275

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