Development, Characterization and Validation of Trastuzumab-Modified Gold Nanoparticles for Molecularly Targeted Radiosensitization of Breast Cance

Development, Characterization and Validation of Trastuzumab-Modified Gold Nanoparticles for Molecularly Targeted Radiosensitization of Breast Cance

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The overexpression of the human epidermal growth factor receptor-2 (HER-2) in 20-25% of human breast cancers was investigated as a target for development of a gold nanoparticle (AuNP) based radiosensitizer for improving the efficacy of neoadjuvant X-radiation therapy of the disease. HER-2 targeted A...

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Bibliographic Details
Main Author: Chattopadhyay, Niladri
Other Authors: Raymond, Reilly
Language:en_ca
Published: 2012
Subjects:
Gold Nanoparticles
Radiation Therapy
Imaging
Antibodies
HER2
Trastuzumab
Radiosensitizer
Breast Cancer
Radionuclide
Nanomedicine
Nanoparticles
Molecular Targeting
0572
0992
0610
0491
0754
0379
0307
0541
Online Access:http://hdl.handle.net/1807/43379

Internet

http://hdl.handle.net/1807/43379

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