Centrosome and Mitotic Spindle Organization in Human Cells

Robust bipolar spindle formation and faithful transmission of genetic material are vital to the maintenance of genome integrity and cellular homeostasis. Chromosome segregation errors can result in aneuploidy, a hallmark of human solid tumors. The assembly of a microtubule-based mitotic spindle reli...

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Bibliographic Details
Main Author: Lawo, Steffen
Other Authors: Pelletier, Laurence
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/43651