Organizing the Ubiquitin-dependent Response to DNA Double-Strand Breaks
DNA double-strand breaks (DSBs) are highly cytolethal DNA lesions. To protect genomic integrity and ensure cellular homeostasis, cells initiate a complex signaling-based response that activates cell cycle checkpoints, coordinates DNA repair, regulates gene expression and, if necessary, induces apopt...
Main Author: | Panier, Stephanie |
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Other Authors: | Durocher, Daniel |
Language: | en_ca |
Published: |
2013
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Subjects: | |
Online Access: | http://hdl.handle.net/1807/43705 |
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