Angiotensin II Proteomic Signature in Human Proximal Tubular Cells as a Predictor of Renin Angiotensin System Activity in Kidney Diseases
Angiotensin II (AngII), the major effector of the renin angiotensin system, mediates kidney disease progression by signalling through AT-1 receptor (AT-1R), but there are no specific measures of renal AngII activity. Accordingly, we sought to define an AngII-regulated proteome in primary human proxi...
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| Language: | en_ca |
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2014
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| Online Access: | http://hdl.handle.net/1807/65676 |