A Novel Reciprocal Regulatory Circuit Between Caspase-8 and c-Src

Apoptosis and cell survival are two seemingly opposing fate-determining processes that are regulated by distinct and complex signaling pathways. Caspase-8, an apical caspase, plays a pivotal regulatory role in initiating apoptosis. c-Src, a prototypical member of the Src family kinases (SFKs), re...

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Bibliographic Details
Main Author: Tsang, Jennifer Lai-Yee
Other Authors: Marshall, John C
Language:en_ca
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1807/65760