Effects of Dietary Protein on Blood Coagulation in Rats

碩士 === 靜宜大學 === 食品營養學系 === 84 === Blood coagulation is accelerated by feeding rats with high protein diet.Hypercoagulability of blood increases the risk of developing cardiovascular disease. The purpose of this project is to study the effect of different...

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Bibliographic Details
Main Authors: Shyong, Pey-Ling, 熊佩玲
Other Authors: Kung-Chi Chan
Format: Others
Language:zh-TW
Published: 1996
Online Access:http://ndltd.ncl.edu.tw/handle/04894146370022501201
Description
Summary:碩士 === 靜宜大學 === 食品營養學系 === 84 === Blood coagulation is accelerated by feeding rats with high protein diet.Hypercoagulability of blood increases the risk of developing cardiovascular disease. The purpose of this project is to study the effect of differentsources and levels of dietary protein on blood coagulation in rats. Three experiments were conducted in this study. Eighty 8 wks old, maleWistar rats were used in all experiments. After 7 days of feeding, bleedingtime and plasma clotting time were determined. Bleeding time was dterminedby a standard procedure. Plasma clotting time and activity of several plasmacoagulation factors were measured by a semi-automatic coagulometer with standard procedured. The results of this study indicated that short-term high protein intakein rats may accelerate the rate of blood coagulation by affecting theabundance or activity of coagulation factors. We also found that low animalprotein and soy protein intake may slowdown the rate of blood coagulation andmay decrease blood lipids. Further studies are warranted to determine whether this decreases the risk of developing cardiovascular disease.