Cloning and Characterization of a Base Excision Repair Enzyme for DNA Containing 7,8-dihydro-8-oxoguanine of human and Mycobacterium tuberculosis

碩士 === 國立臺灣大學 === 分子醫學研究所 === 87 === The guanine modification 7,8-dihydro-8-oxoguanine (8-oxoG) on the genomic DNA is a potent premutagenic lesion produced by reactive oxygen species. This type of lesion is removed by 8-oxoguanine glycosylase (Ogg1) in yeast and the cDNA of human 8-oxogua...

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Bibliographic Details
Main Authors: Lee, Wei-Sheng, 李威昇
Other Authors: C.H. Herbert Wu
Format: Others
Language:en_US
Published: 1999
Online Access:http://ndltd.ncl.edu.tw/handle/88927832693901631511