Preparation of Thiazinone, Benzothiazinone and Tricyclic Benzothiazinone Compounds and Evaluation of Their Xanthine
碩士 === 台北醫學院 === 藥學研究所 === 87 === In a previous study, we found that benzothiazinone compounds displayed a significant inhibition on xanthine oxidase in in vitro test. 2-Amino-4H-1,3-benzothiazin-4-one (BJ-6) (IC50 = 5.54μM, Ki = 5.12μM) and 4-oxo-4H-1,3-benzothiazinone-2-guanidine (TDW-1) (IC50 = 5...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
1999
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| Online Access: | http://ndltd.ncl.edu.tw/handle/02627303636099071397 |