1. Syntheses and Opioid Activity of Spiro[benzofuran-3(2H),4’-piperidines] : A Conformation-activity Study and Novel Synthesis of Isoneopine : A Formal Total Synthesis of Morphine
博士 === 國立臺灣大學 === 藥學研究所 === 88 === Approaches based on simplification of the pentacyclic morphine skeleton towards the discovery of novel analgesics have been adopted by generations of medicinal chemists. However, the tricyclic spiro[benzofuran-3(2H),4’-piperidines], morphine ANO fragments, have nev...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | zh-TW |
Published: |
2000
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Online Access: | http://ndltd.ncl.edu.tw/handle/61170371995587220133 |