Synthesis of 15N and 13C labelled pyrimethamine and study its dihydrofolate reductase complexe

碩士 === 國立成功大學 === 化學系 === 89 === [ 2-13C]- and [1,3,2-NH2 -15N3]- pyrimethamine have been synthesized according to the reported methods with some modification. 13C- and 15N-NMR techniques have been used to study its Escherichia coli dihydrofolate reductase (DHFR) complexes. Under the pH...

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Bibliographic Details
Main Authors: Feng Ying Chen, 陳鳳英
Other Authors: Fu Yung Huang
Format: Others
Language:zh-TW
Published: 2001
Online Access:http://ndltd.ncl.edu.tw/handle/79448202189933676738