Structural Studies of SH3 and SH2 Domain of Bruton’s Tyrosine Kinase

博士 === 國立清華大學 === 生命科學系 === 89 === X-linked agammaglobulinemia (XLA) is caused by mutations in the Bruton''s tyrosine kinase (BTK). Point mutation in the BTK gene that leads to deletion of C-terminal 14 aa residues of BTK SH3 domain was found in a patient family. We studied binding of BTK...

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Bibliographic Details
Main Authors: TZENG, SHIOU-RU, 曾秀如
Other Authors: CHENG, JYA-WEI
Format: Others
Language:en_US
Published: 2001
Online Access:http://ndltd.ncl.edu.tw/handle/83112458819878210808