Study of pathogfenic effects of expanded CTG trinucleotide repeats on the muscle function of C. elegans

碩士 === 中山醫學大學 === 醫學研究所 === 90 === Expansion mutation of CTG repeat length in the 3’-untranslated region of human DMPK gene causes a dominantly inherited muscular disease, called myotonic dystrophy type1 (DM1). In this study we attempt to establish a DM1-disease animal model using transge...

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Bibliographic Details
Main Authors: Shu-Ya Chiang, 江淑雅
Other Authors: Kuang-Ming Hsaio
Format: Others
Language:zh-TW
Published: 2002
Online Access:http://ndltd.ncl.edu.tw/handle/88412193524330023008